4-(1,3,4-Oxadiazol-2-yl)phenol
CAS: 5378-27-8
Ref. 3D-FAA37827
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Información del producto
4-(1,3,4-Oxadiazol-2-yl)phenol (ODOP) is a potent and selective apoptosis inducer that causes the death of cancer cells by generating reactive oxygen species. ODOP activates polyphosphoric acid in the mitochondria to form reactive oxygen species. The cytotoxicity of ODOP is dose-dependent and can be reconfirmed by nucleophilic attack on DNA. ODOP has been shown to have pharmacokinetic properties that are similar to those of other drugs in the same class, such as acylhydrazides. These drugs are rapidly metabolized by esterases or glucuronidases in vivo and are excreted mainly through urine.
Propiedades químicas
Consulta técnica sobre: 3D-FAA37827 4-(1,3,4-Oxadiazol-2-yl)phenol
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