5-{[7-(Benzyloxy)-4-Quinazolinyl]Amino}-4-Fluoro-2-Methylphenol Hydrochloride (1:1)

CAS: 193001-14-8

Ref. 3D-FB101016

Información del producto

• Nombre: 5-{[7-(Benzyloxy)-4-Quinazolinyl]Amino}-4-Fluoro-2-Methylphenol Hydrochloride (1:1)

Descripción

5-{[7-(Benzyloxy)-4-Quinazolinyl]Amino}-4-Fluoro-2-Methylphenol Hydrochloride (1:1) is a benzyl ether that has a strong inhibitory effect on the growth of endothelial cells and is used as an anti-angiogenic agent. It binds to the receptor for angiogenesis, which is composed of two subunits, one of which is the protein tyrosine kinase receptor. The other subunit is the extracellular matrix protein fibronectin. This binding inhibits endothelial cell proliferation by inhibiting the signalling pathway of vascular endothelial growth factor (VEGF). The benzyl group also has an antagonist effect on class II histocompatibility antigen, so this drug may be useful in treating autoimmune disorders such as arthritis or diabetes.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 411.86 g/mol
• Fórmula: C₂₂H₁₉ClFN₃O₂
• Pureza: Min. 95%