Nelotanserin

CAS: 839713-36-9

Ref. 3D-FB101032

Información del producto

• Nombre: Nelotanserin
• Sinónimos: 1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea, 1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea, APD 125, N-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-N′-(2,4-difluorophenyl)urea, 1-(2,4-Difluorophenyl)-3-[4-methoxy-3-(4-bromo-1-methyl-1H-pyrazol-5-yl)phenyl]urea, Urea, N-[3-(4-bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-N′-(2,4-difluorophenyl)-

Descripción

1-[3-(4-Bromo-1-methyl-1H-pyrazol-5-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea is the active ingredient in a drug that is used to treat chronic schizophrenia. It has been shown to have both antipsychotic and antidepressant properties. The drug works by blocking the 5HT2A receptor, which inhibits the effects of serotonin on heterocyclic amines at the postsynaptic membrane. This causes hyperpolarization of the membrane, which blocks neurotransmitter release and prevents further transmission of signals. It also blocks the H1 receptor, which decreases histamine release and reduces inflammation in the brain.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 437.24 g/mol
• Fórmula: C₁₈H₁₅BrF₂N₄O₂
• Pureza: Min. 95%
• Color/Forma: Powder
• InChI: InChI=1S/C18H15BrF2N4O2/c1-25-17(13(19)9-22-25)12-8-11(4-6-16(12)27-2)23-18(26)24-15-5-3-10(20)7-14(15)21/h3-9H,1-2H3,(H2,23,24,26)
• Clave InChI: InChIKey=COSPVUFTLGQDQL-UHFFFAOYSA-N
• SMILES: COc1ccc(NC(=O)Nc2ccc(F)cc2F)cc1-c1c(Br)cnn1C