1-Benzothiophene-3-carbohydrazide

CAS: 78676-34-3

Ref. 3D-FB114131

Información del producto

• Nombre: 1-Benzothiophene-3-carbohydrazide
• Sinónimos: Benzo[B]Thiophene-3-Carboxylic Acid, Hydrazide

Descripción

1-Benzothiophene-3-carbohydrazide (1BZC) is a small molecule that inhibits the growth of cancer cells. It acts by inhibiting the protein kinase pim-1, which is necessary for many cellular processes, including cell proliferation and cell adhesion. 1BZC has been shown to inhibit tumor growth in vivo, as well as in vitro in cancer cell lines and mouse xenografts. The drug has also been shown to disrupt tumor vascularization by targeting the protein vegfr-2. 1BZC has also been shown to be effective against two different human cancers: MDA-MB231 breast cancer cells and MKN45 gastric cancer cells. The drug has anti-proliferative activity against both cell lines and inhibits the growth of MDA-MB231 cells more than MKN45 cells.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 192.24 g/mol
• Fórmula: C₉H₈N₂OS
• Pureza: Min. 95 Area-%
• Color/Forma: Powder
• InChI: InChI=1S/C9H8N2OS/c10-11-9(12)7-5-13-8-4-2-1-3-6(7)8/h1-5H,10H2,(H,11,12)
• Clave InChI: InChIKey=WISUPLDFMRTYAJ-UHFFFAOYSA-N
• SMILES: NNC(=O)c1csc2ccccc12