N-Boc-D-allylglycine

CAS: 170899-08-8

Ref. 3D-FB12005

Información del producto

• Nombre: N-Boc-D-allylglycine
• Sinónimos: Boc-(R)-2-Allylglycine, (R)-N-tert-Butoxycarbonyl-2-amino-4-pentenoic acid, (2R)-2-[(tert-butoxycarbonyl)amino]pent-4-enoate, (2R)-2-[(tert-butoxycarbonyl)amino]pent-4-enoic acid-N-cyclohexylcyclohexanamine (1:1), Boc-D-Allylglycine.DCHA, Boc-D-Allylglycine

Descripción

N-Boc-D-allylglycine is a peptidomimetic drug that inhibits caspase-3, an enzyme involved in apoptosis. This drug has been shown to inhibit the proteolytic activity of caspase-3 and thereby inhibit the induction of cell death by various stimuli. N-Boc-D-allylglycine is orally bioavailable and is metabolized into two active analogs: N-(2-(N′-(allyloxycarbonyl)-L-alanyl))glycine (NAGL) and N′-(2-(N′-(allyloxycarbonyl)-L-alanyl))glycinamide (NAG). These active analogs are potent inhibitors of caspase-3, with more than 100 times the potency of the parent compound. This compound also has a prodrug form, which can be hydrolyzed by esterases or glucuronidases to release the active form

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 215.25 g/mol
• Fórmula: C₁₀H₁₇NO₄
• Pureza: Min. 95%
• Color/Forma: Powder