N-Boc-D-allylglycine

CAS: 170899-08-8

Ref. 3D-FB12005

Información del producto

• Nombre: N-Boc-D-allylglycine
• Marca: Biosynth
• Descripción: N-Boc-D-allylglycine is a peptidomimetic drug that inhibits caspase-3, an enzyme involved in apoptosis. This drug has been shown to inhibit the proteolytic activity of caspase-3 and thereby inhibit the induction of cell death by various stimuli. N-Boc-D-allylglycine is orally bioavailable and is metabolized into two active analogs: N-(2-(N′-(allyloxycarbonyl)-L-alanyl))glycine (NAGL) and N′-(2-(N′-(allyloxycarbonyl)-L-alanyl))glycinamide (NAG). These active analogs are potent inhibitors of caspase-3, with more than 100 times the potency of the parent compound. This compound also has a prodrug form, which can be hydrolyzed by esterases or glucuronidases to release the active form

Propiedades químicas

• Peso molecular: 215.25 g/mol
• Fórmula: C₁₀H₁₇NO₄
• Pureza: Min. 95%
• Color/Forma: Powder