2-Bromo-5-fluorobenzoic acid

CAS: 394-28-5

Ref. 3D-FB12070

Información del producto

• Nombre: 2-Bromo-5-fluorobenzoic acid
• Sinónimos: 2-Bromo-5-Fluorobenzoate, 2-Bromo-5-Fluorobenzoic, 2-Bromo-5-Fluorobenzoicacid,98%, 2-Bromo-5-fluorobenzoic acid,98%, 5-Fluoro-2-bromobenzoic acid, Benzoic acid, 2-bromo-5-fluoro-, Buttpark 19\01-66, Rarechem Al Bo 0747
• CAS: 394-28-5

Descripción

2-Bromo-5-fluorobenzoic acid is a polymerase inhibitor that inhibits the activity of the HIV-1 reverse transcriptase by competitive inhibition. It prevents the synthesis of viral DNA by binding to the RNA template and preventing chain elongation. This drug has been shown to be an effective treatment for some types of cancer, such as lung cancer, because it is not easily metabolized and can therefore reach high concentrations in tissues where it is needed. 2-Bromo-5-fluorobenzoic acid is synthesized from 5-(2′-bromophenoxy)benzothiazole and 2,3,4,5,6-pentafluorobenzoyl chloride in three steps. The synthesis involves bromination of benzothiazole with NBS followed by reaction with 4-fluoroaniline to give the intermediate which is then reacted with pentafluorobenzoyl chloride. This compound

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 219.01 g/mol
• Fórmula: C₇H₄BrFO₂
• Pureza: Min. 95%
• Color/Forma: Powder
• InChI: InChI=1S/C7H4BrFO2/c8-6-2-1-4(9)3-5(6)7(10)11/h1-3H,(H,10,11)
• Clave InChI: InChIKey=OQBMJMJZMDBQSM-UHFFFAOYSA-N
• SMILES: O=C(O)c1cc(F)ccc1Br