tert-Butyl 4-bromo-1H-indole-1-carboxylate

CAS: 676448-17-2

Ref. 3D-FB139486

Información del producto

• Nombre: tert-Butyl 4-bromo-1H-indole-1-carboxylate
• Sinónimos: tert-butyl-4-bromo-1H-indole-1-carboxylate, Tert-Butyl 4-Bromoindole-1-Carboxylate

Descripción

tert-Butyl 4-bromo-1H-indole-1-carboxylate is a low temperature, synthetic compound that has been used to synthesize welwitindolinone derivatives. A novel functionalized tertiary alcohol was prepared by the alkylation of a tertiary amine with 2,4,6-trichlorobenzoyl chloride. The reaction proceeded smoothly at room temperature and afforded the desired product in good yield. The cyclization of this tertiary alcohol with an intramolecular nucleophile (cycloadduct) led to the formation of a bicyclic furan derivative. This reaction was stereoselective and gave high yields for both steps.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 296.16 g/mol
• Fórmula: C₁₃H₁₄BrNO₂
• Pureza: Min. 95%
• InChI: InChI=1S/C13H14BrNO2/c1-13(2,3)17-12(16)15-8-7-9-10(14)5-4-6-11(9)15/h4-8H,1-3H3
• Clave InChI: InChIKey=ZGBNKNOAADXGOH-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)n1ccc2c(Br)cccc21