3-Bromopiperidin-2-one
CAS: 34433-86-8
Ref. 3D-FB143793
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Información del producto
- 2-Piperidinone, 3-bromo-
- 3-Bromo-2-piperidinone
- 3-Bromo-2-piperidone
- α-Bromovalerolactam
- 2-Piperidone, 3-bromo-
3-Bromopiperidin-2-one is a chemical compound with the molecular formula CHBrClO. 3-Bromopiperidin-2-one is synthesized from coniferyl alcohol and chloroacetyl chloride in the presence of phosphorus pentachloride. The reaction product is purified by chromatography on silica gel and recrystallization from ethyl acetate to yield 3-bromopiperidin-2-one as a white solid. The enantiopure synthesis of 3-bromopiperidin-2-one requires the use of an immobilized lipase, which catalyzes the hydrolysis of ester bonds in the aryl ester intermediate, producing a chemoenzymatic synthesis.
3-Bromopiperidin-2-one can be used as a chemical reagent for various reactions, such as arylation, thionylation, or organocup
Propiedades químicas
Consulta técnica sobre: 3D-FB143793 3-Bromopiperidin-2-one
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