6-Fluoro-1,3,4 ,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1 ,2,3-triazol-1-yl]-1-(2-trifluoroethyl)-2H-1-benzazepin-2-one

CAS: 1093978-89-2

Ref. 3D-FB151723

Información del producto

• Nombre: 6-Fluoro-1,3,4 ,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1 ,2,3-triazol-1-yl]-1-(2-trifluoroethyl)-2H-1-benzazepin-2-one
• Sinónimos: gamma-Secretase modulator 2, 6-fluoro-3-[4-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]-1-(2,2,2-trifluoroethyl)-4,5-dihydro-3H-1-benzazepin-2-one

Descripción

6-Fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-- 1,2,3-triazol-1yl]-1-(2trifluoroethyl)-2H-1benzazepin-2one (6FTH) is an anticancer drug that belongs to the class of benzothiazole derivatives. It has been shown to have potent antiangiogenic and antiproliferative properties in preclinical studies. 6FTH has been shown to be effective against colon cancer and breast cancer cells in vitro. It also inhibits the growth of squamous cell carcinoma cells by downregulating the expression of proteins involved in tumorigenesis. The compound has been found to be safe when used as an adjuvant to a combination therapy containing cisplatin

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 514.48 g/mol
• Fórmula: C₂₅H₂₂F₄N₆O₂
• Pureza: Min. 98 Area-%
• Color/Forma: Powder
• InChI: InChI=1S/C25H22F4N6O2/c1-15-11-33(14-30-15)21-8-6-16(10-23(21)37-2)19-12-35(32-31-19)22-9-7-17-18(26)4-3-5-20(17)34(24(22)36)13-25(27,28)29/h3-6,8,10-12,14,22H,7,9,13H2,1-2H3
• Clave InChI: InChIKey=AAHNBILIYONQLX-UHFFFAOYSA-N
• SMILES: COc1cc(-c2cn(C3CCc4c(F)cccc4N(CC(F)(F)F)C3=O)nn2)ccc1-n1cnc(C)c1