BOP-Cl

CAS: 68641-49-6

Ref. 3D-FB15576

Información del producto

• Nombre: BOP-Cl
• Sinónimos: Bis(2-oxo-3-oxazolidinyl)phosphinic chloridePhosphoric acid bis(2-oxooxazolidide) chloride, Bis(2-Oxo-1,3-Oxazolidin-3-Yl)Phosphinic Chloride, Bis(2-oxo-3-oxazolidiny)phosphonic chloride, Bis(2-oxo-3-oxazolidinyl)phosphoryl chloride, Bop-Cl, Bopdc, NSC 377647, P,P-Bis(2-oxo-3-oxazolidinyl)phosphinic chloride, Phosphinic chloride, P,P-bis(2-oxo-3-oxazolidinyl)-, Phosphinic chloride, bis(2-oxo-3-oxazolidinyl)-

Descripción

BOP-Cl is a phosphoric acid derivative used as a coupling reagent for amide and ester formation. BOP-Cl is effective in the acylation of N-methylated amino acids and in the introduction of thiopeptide bonds on imino acids. BOP-Cl requires mild conditions, gives good yields and suppresses epimerisation. BOP-Cl and other phosphinic acids activate the carboxylic acid by forming a carboxylic-phosphinic mixed anhydride, in which stereochemistry is conveniently retained. BOP-Cl gives good performances in the acylation of N-methylated amino acids due to intramolecular base catalysis.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 254.56 g/mol
• Fórmula: C₆H₈ClN₂O₅P
• Pureza: Min. 95%
• Color/Forma: Powder
• InChI: InChI=1S/C6H8ClN2O5P/c7-15(12,8-1-3-13-5(8)10)9-2-4-14-6(9)11/h1-4H2
• Clave InChI: InChIKey=KLDLRDSRCMJKGM-UHFFFAOYSA-N
• SMILES: O=C1OCCN1P(=O)(Cl)N1CCOC1=O