(+/-)-Butoxamine

CAS: 1937-89-9

Ref. 3D-FB158959

Información del producto

• Nombre: (+/-)-Butoxamine
• Sinónimos: (1R,2S)-2-(tert-Butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol, (1R,2S)-2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol, (R*,S*)-(+-)-alpha-(1-((1,1-Dimethylethyl)amino)ethyl)-2,5-dimethoxybenzenemethanol, Benzenemethanol, alpha-((1R)-1-((1,1-dimethylethyl)amino)ethyl)-2,5-dimethoxy-, (alphaS)-rel-, Benzenemethanol, alpha-(1-((1,1-dimethylethyl)amino)ethyl)-2,5-dimethoxy-, (R*,S*)-(+-)-, Benzenemethanol, α-[(1R)-1-[(1,1-dimethylethyl)amino]ethyl]-2,5-dimethoxy-, (αS)-rel-, Benzenemethanol, α-[1-[(1,1-dimethylethyl)amino]ethyl]-2,5-dimethoxy-, (R*,S*)-, Benzyl alcohol, alpha-(1-(tert-butylamino)ethyl)-2,5-dimethoxy-, DL-erythro-, Benzyl alcohol, α-[1-(tert-butylamino)ethyl]-2,5-dimethoxy-, <span class="text-smallcaps">DL</span>-erythro-, Butaxamina [INN-Spanish], Butaxamine, Butaxaminum [INN-Latin], Butoxamine [INN], rel-(αS)-α-[(1R)-1-[(1,1-Dimethylethyl)amino]ethyl]-2,5-dimethoxybenzenemethanol

Descripción

Butoxamine is a 5-HT1A receptor agonist that has been shown to activate cardiac 2-adrenergic receptors. It also inhibits ATP-sensitive K+ channels in the heart, thereby inhibiting cardiac excitability and promoting relaxation. Butoxamine has been shown to have anticholinergic effects on the detrusor muscle of the bladder, as well as other effects on smooth muscle. The ester hydrochloride salt of butoxamine has been used in polymerase chain reaction (PCR) studies for its ability to bind single-stranded DNA templates. The drug also inhibits bacterial translocation by blocking bacterial DNA gyrase, an enzyme that maintains the integrity of bacterial DNA. Butoxamine is also a cyclase inhibitor, which prevents the production of cAMP from ATP. This inhibition leads to reduced levels of phosphodiesterase and may have anti-inflammatory effects.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 267.36 g/mol
• Fórmula: C₁₅H₂₅NO₃
• Pureza: Min. 95%
• InChI: InChI=1S/C15H25NO3/c1-10(16-15(2,3)4)14(17)12-9-11(18-5)7-8-13(12)19-6/h7-10,14,16-17H,1-6H3/t10-,14-/m1/s1
• Clave InChI: InChIKey=TWUSDDMONZULSC-QMTHXVAHSA-N
• SMILES: COc1ccc(OC)c([C@H](O)[C@@H](C)NC(C)(C)C)c1