3-O-Benzyl estrone

CAS: 858-98-0

Ref. 3D-FB18293

Información del producto

• Nombre: 3-O-Benzyl estrone
• Sinónimos: 3-(Phenylmethoxy)-estra-1,3,5(10)-trien-17-one3-(Benzyloxy)-estra-1,3,5(10)-trien-17-one3-(Benzyloxy)estra-1,3,5(10)-trien-17-one
• Marca: Biosynth

Descripción

3-O-Benzyl estrone is a boron trifluoride etherate that has been investigated as a radiolabeled estrogen receptor alpha agonist. 3-O-Benzyl estrone has been shown to be an effective cancer therapy in the treatment of breast, colon, and skin cancers. It also has anti-inflammatory properties by inhibiting cytokine production. The chemical structure of 3-O-Benzyl estrone is an estradiol amide with a benzene ring in the ortho position. The heterocycle is substituted with three fluorines at the 3, 4, and 5 positions. This estrogenic agent is prepared via the reduction of borohydride with hydrogen gas. 3-O-Benzyl estrone binds to the estrogen receptor alpha and inhibits protein synthesis by binding to DNA at specific sites on the gene promoter region.

Propiedades químicas

• Peso molecular: 360.49 g/mol
• Fórmula: C₂₅H₂₈O₂
• Pureza: Min. 95%