N-t-Boc-L-proline-N-hydroxysuccinimide ester

CAS: 3392-10-7

Ref. 3D-FB18959

Información del producto

• Nombre: N-t-Boc-L-proline-N-hydroxysuccinimide ester
• Sinónimos: (2S)-1,2-Pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) 2-(2,5-dioxo-1-pyrrolidinyl) ester(2S)-2-[[(2,5-Dioxo-1-pyrrolidinyl)ox y]carbonyl]-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester, 1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) 2-(2,5-dioxo-1-pyrrolidinyl) ester, (2S)-, 1,2-Pyrrolidinedicarboxylic acid, 1-tert-butyl ester, succinimido deriv., <span class="text-smallcaps">L</span>-, 1-O-tert-Butyl 2-O-(2,5-dioxopyrrolidin-1-yl) (2S)-pyrrolidine-1,2-dicarboxylate, 1-Pyrrolidinecarboxylic acid, 2-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-, 1,1-dimethylethyl ester, (2S)-, 1-Pyrrolidinecarboxylic acid, 2-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-, 1,1-dimethylethyl ester, (S)-, 2,5-Dioxopyrrolidin-1-Yl 1-(Tert-Butoxycarbonyl)Prolinate, 2,5-dioxopyrrolidin-1-yl 1-(tert-butoxycarbonyl)-L-prolinate, Boc-Pro-OSu, N-Boc-<span class="text-smallcaps">L</span>-proline N-hydroxysuccinimidyl ester, N-T-boc-L-proline N-*hydroxysuccinimide ester, Succinimide, N-[(1-carboxy-<span class="text-smallcaps">L</span>-prolyl)oxy]-, tert-butyl ester, 1,2-Pyrrolidinedicarboxylic acid, 1-tert-butyl ester, succinimido deriv., L-, Succinimide, N-[(1-carboxy-L-prolyl)oxy]-, tert-butyl ester

Descripción

N-t-Boc-L-proline-N-hydroxysuccinimide ester is a histidine derivative that has been shown to be an effective inhibitor of serine protease. It is used as a substrate analogue for the study of influenza virus and glycosidases. The reaction yield was increased by using trifluoroacetic acid, which is more reactive than hydrochloric acid, in the synthesis of N-t-Boc-L-proline-N-hydroxysuccinimide ester. One drawback to this method is that it requires a solid phase synthesis due to its insolubility in water. This product is also acetylated at the nitrogen atom on the side chain, which may increase its stability and reduce its reactivity with nucleophiles.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 312.32 g/mol
• Fórmula: C₁₄H₂₀N₂O₆
• Pureza: Min. 95%
• InChI: InChI=1S/C14H20N2O6/c1-14(2,3)21-13(20)15-8-4-5-9(15)12(19)22-16-10(17)6-7-11(16)18/h9H,4-8H2,1-3H3/t9-/m0/s1
• Clave InChI: InChIKey=DICWIJISMKZDDY-VIFPVBQESA-N
• SMILES: CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)ON1C(=O)CCC1=O