N-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide
CAS: 127243-85-0
Ref. 3D-FB19217
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Información del producto
- N-[2-[[3-(4-Bromophenyl)-2-propen-1-yl]amino]ethyl]-5-isoquinolinesulfonamideH-89
- 5-Isoquinolinesulfonamide, N-(2-((3-(4-bromophenyl)-2-propenyl)amino)ethyl)-
- 5-Isoquinolinesulfonamide, N-[2-[[3-(4-bromophenyl)-2-propen-1-yl]amino]ethyl]-
- H 89 (pharmaceutical)
- H-89
- H-89 Dihydrochloride Hydrate
- H-89 Hydrochloride
- H-89 hydrate dihydrochloride
- H89
- IQB
- Ver más sinónimos
- N-(2-((3-(4-Bromophenyl)-2-propenyl)amino)ehtyl)-5-isoquinolinesulfonamide dihydrochloride
- N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide
- N-(2-[P-Bromocinnamylamino]Ethyl)-5-Isoquinolinesulfonamide Hydrochloride
- N-(2-{[(2E)-3-(4-bromophenyl)prop-2-en-1-yl]amino}ethyl)isoquinoline-5-sulfonamide
- N-(2-{[(2E)-3-(4-bromophenyl)prop-2-en-1-yl]amino}ethyl)isoquinoline-5-sulfonamide dihydrochloride
- N-[2-(4-Bromocinnamylamino)Ethyl]-5-Isoquinoline Sulfonamide
- N-[2-(P-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE dihydrochloride
- N-[2-(P-Bromocinnamylamino)Ethyl]-5-Isoquinolinesulfonamide 2Hcl
- N-[2-[P-Bromocinnamylamino]-Ethyl]-5-Isoquinolinesulfonmide
- N-[2-[[(E)-3-(4-bromophenyl)prop-2-enyl]amino]ethyl]isoquinoline-5-sulfonamide
- N-[2-[[3-(4-Bromophenyl)-2-propen-1-yl]amino]ethyl]-5-isoquinolinesulfonamide
- Protein kinase inhibitor H89
N-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide (BQCA) is a potent inhibitor of protein kinase C. It has been shown to inhibit the activation of Ca2+/calmodulin-dependent protein kinase II in rat hippocampal neurons and to inhibit Ca2+/calmodulin-dependent protein kinase IV in bovine brain. BQCA blocks the phosphorylation of epidermal growth factor receptor and inhibits its downstream signaling pathways, leading to neuronal death. This drug has also been shown to inhibit the activity of other serine/threonine kinases, such as PKC, PKD, Raf1, MEK1, MEK2, and p38 MAPK.
Propiedades químicas
Consulta técnica sobre: 3D-FB19217 N-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide
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