(E)-2-(1-Butenyl)-1,3,2-benzodioxaborole

CAS: 106094-36-4

Ref. 3D-FB19381

Información del producto

• Nombre: (E)-2-(1-Butenyl)-1,3,2-benzodioxaborole
• Sinónimos: 2-(1E)-1-Butenyl-1,3,2-benzodioxaborole

Descripción

(E)-2-(1-Butenyl)-1,3,2-benzodioxaborole is a novel glycogen synthase inhibitor that has been shown to be effective in diabetic animal models. It was found to inhibit the activity of glycogen phosphorylase and increase the level of glycogen in the liver. (E)-2-(1-Butenyl)-1,3,2-benzodioxaborole has been optimized by replacing one or more of its moieties with anthranilimide groups. This replacement increases potency by 2 orders of magnitude with nanomolar potency. (E)-2-(1-Butenyl)-1,3,2-benzodioxaborole inhibits xanthine oxidase and xanthine dehydrogenase enzymes and prevents the formation of uric acid from xanthine during purine metabolism. It also inhibits glycolysis and glucose production through inhibition of phosphofructokinase 1.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 174 g/mol
• Fórmula: C₁₀H₁₁BO₂
• Pureza: Min. 95%
• Color/Forma: Powder
• InChI: InChI=1S/C10H11BO2/c1-2-3-8-11-12-9-6-4-5-7-10(9)13-11/h3-8H,2H2,1H3/b8-3+
• Clave InChI: InChIKey=QTICDYDCSGBDQP-FPYGCLRLSA-N
• SMILES: CC/C=C/B1Oc2ccccc2O1