5-(Bromoacetyl)-2-hydroxybenzamide

CAS: 73866-23-6

Ref. 3D-FB38913

Información del producto

• Nombre: 5-(Bromoacetyl)-2-hydroxybenzamide
• Sinónimos: 5-(2-Bromoacetyl)-2-hydroxybenzamide, 5-Bromo Acetyl Salicylamide, 5-Bromoacetyl Salicylamide, 5-Bromoacetylsalicylamide, 5-Bromoacetylsalicyliclamide, Benzamide, 5-(2-bromoacetyl)-2-hydroxy-, Benzamide, 5-(bromoacetyl)-2-hydroxy-, 5-Bromoacetyl-2-hydroxybenzamide

Descripción

5-(Bromoacetyl)-2-hydroxybenzamide (BAC) is a brominated compound that has been shown to lower fasting blood glucose level in diabetic rats. It also prevents weight gain and improves insulin sensitivity in rats fed a high-fat diet. This drug has been found to be nontoxic for the liver and kidneys, even at high doses. BAC is a type of nucleophilic inhibitor that binds to the hydroxyl group of the substrate and converts it into an alcohol. The molecule is then converted by ammonolysis into an amide or amine. BAC inhibits the enzyme monoamine oxidase, which is involved in the metabolism of neurotransmitters such as dopamine, norepinephrine, serotonin, and melatonin. BAC also acts as a type-2 diabetes drug by increasing insulin secretion and reducing glucose production by the liver.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 258.07 g/mol
• Fórmula: C₉H₈BrNO₃
• Pureza: Min. 95 Area-%
• Color/Forma: Powder