4-Bromo-5-nitroisoQuinoline
CAS: 58142-46-4
Ref. 3D-FB40668
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Información del producto
- 4-Bromo-5-nitro-isoquinoline
- Isoquinoline, 4-Bromo-5-Nitro-
4-Bromo-5-nitroisoQuinoline is a drug that has been tested for use in the treatment of Parkinson's disease. 4-Bromo-5-nitroisoQuinoline is an isoform selective ligand with high affinity for dopamine D3 and D4 receptors, but not for dopamine D2 receptors. It also binds to sodium carbonate, hydrochloric acid, and ligands with affinity for d3 receptors and d4 receptor. The pharmacophore model of 4-Bromo-5-nitroisoQuinoline is as follows:
The pharmacological activity of 4-Bromo-5-nitroisoQuinoline may be due to its ability to inhibit the release of dopamine from neurons by binding to the serotonin transporter on presynaptic terminals or by increasing the duration of dopamine action at postsynaptic sites.
Propiedades químicas
Consulta técnica sobre: 3D-FB40668 4-Bromo-5-nitroisoQuinoline
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