3-Bromo-4-methylbenzoic acid
CAS: 7697-26-9
Ref. 3D-FB45071
1kg | 1.403,00 € | ||
2kg | 2.614,00 € | ||
5kg | 6.105,00 € | ||
250g | 311,00 € | ||
500g | 470,00 € |
Información del producto
- 3-Bromo-4-Methylbenzoate
- 3-Bromo-4-Methylbenzoicacid
- 3-Bromo-4-methylbenzenecarboxylic acid
- 3-Bromo-p-toluic acid
- 3-Bromo-p-toluic acid (COOH=1)
- 4-Methyl -3-Bromobenzoic acid
- Benzoic acid, 3-bromo-4-methyl-
- NSC 243715
- p-Toluic acid, 3-bromo-
3-Bromo-4-methylbenzoic acid is a labile chemical compound that is used in the synthesis of retinoic acid, an analog of vitamin A. 3-Bromo-4-methylbenzoic acid can be synthesized by a two step process involving the boronic ester and biphenyl. The biphenyl is first treated with phosphorus pentachloride to produce a phenoxyacetate which reacts with 3-bromo-4-methylbenzoyl chloride in the presence of base to produce 3-bromo-4-methylbenzoic acid. This conversion can also be done via a solid phase synthesis where the biphenyl is anchored on silica gel and reacted with 3-bromo-4 methylbenzoyl chloride. The boronic esters are then cleaved from the solid support by treatment with sodium hydroxide under reflux conditions.
3 - Bromo -
Propiedades químicas
Consulta técnica sobre: 3D-FB45071 3-Bromo-4-methylbenzoic acid
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