(1R,2S)-1-(6-Bromo-2-methoxyquinolin-3-yl) -4-(dimethylamino)-2-(naphthalen-1-yl) -1-phenylbutan-2-ol

CAS: 843663-66-1

Ref. 3D-FB46540

Información del producto

• Nombre: (1R,2S)-1-(6-Bromo-2-methoxyquinolin-3-yl) -4-(dimethylamino)-2-(naphthalen-1-yl) -1-phenylbutan-2-ol
• Sinónimos: Bedaquiline, (αS,βR)-6-Bromo-α-[2-(dimethylamino)ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl-3-quinolineethanol, 3-Quinolineethanol, 6-bromo-α-[2-(dimethylamino)ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl-, (αS,βR)-, 6-Bromo-alpha-[2-(dimethylamino)ethyl]-2-methoxy-alpha-1-naphthalenyl-beta-phenyl-3-quinolineethanol, R-207910, Sirturo, Tmc-207

Descripción

Bedaquiline is a drug that inhibits the synthesis of mycobacterial RNA by binding to the ribosomal subunit. It is used to treat tuberculosis and multidrug-resistant tuberculosis. Bedaquiline has been shown to be bactericidal against wild-type strains of Mycobacterium tuberculosis and Mycobacterium avium complex, but not against multidrug-resistant strains of these bacteria. Bedaquiline also interacts with other drugs that inhibit the cytochrome P450 system, such as cycloserine or rifampin. Bedaquiline is active against MDR-TB but not against extensively drug resistant TB (XDR-TB).

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 555.5 g/mol
• Fórmula: C₃₂H₃₁BrN₂O₂
• Pureza: Min. 95%
• Color/Forma: White Powder