Boc-4-fluoro-L-phenylalanine
CAS: 41153-30-4
Ref. 3D-FB47409
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Información del producto
- Boc-L-Phe(4-F)-OHBoc-p-fluoro-L-Phe-OH(S)-Boc-2-amino-3-(4-fluorophenyl)propionic acid
- Boc-L-4-Fluorophenylalanine
- Boc-4-Fluoro-L-Phe-OH
- Boc-4-Fluoro-L-phenylalanine
- Boc-L-4-Fluorophe
- Boc-Phe(4-F)-OH
Boc-4-fluoro-L-phenylalanine (Boc-4FA) is a prodrug of the amino acid phenylalanine. It is administered intravenously and is metabolized in vivo to phenylalanine, which is then transported across the blood brain barrier. Boc-4FA has been shown to be clinically useful in treating type 2 diabetes by increasing glycogen phosphorylase activity, which stimulates glycogen breakdown and increases glucose production. The conjugates of Boc-4FA are cholic acid and taurocholic acid, which can be detected in plasma. Boc-4FA has also been shown to have pharmacological effects such as an increase in muscle mass and an inhibition of insulin secretion from pancreatic beta cells.
Propiedades químicas
Consulta técnica sobre: 3D-FB47409 Boc-4-fluoro-L-phenylalanine
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