Boc-S-trityl-L-homocysteine

CAS: 201419-16-1

Ref. 3D-FB47898

Información del producto

• Nombre: Boc-S-trityl-L-homocysteine
• Sinónimos: Boc-L-HomoCys(Trt)-OH(S)-2-(Boc-amino)-4-tritylsulfanylbutyric acid, N-[(1,1-Dimethylethoxy)carbonyl]-S-(triphenylmethyl)-L-homocysteine, N-tert-Butoxycarbonyl-S-trityl-L-homocysteine, (S)-2-((tert-Butoxycarbonyl)amino)-4-(tritylthio)butanoic acid, L-Homocysteine, N-[(1,1-dimethylethoxy)carbonyl]-S-(triphenylmethyl)-

Descripción

Boc-S-trityl-L-homocysteine is a synthetic molecule that is used as a prodrug to introduce the amino acid homocysteine into cells. It has been shown to have anti-cancer and estrogen receptor modulating properties. Boc-S-trityl-L-homocysteine is synthesized by reacting L-homocysteine with diisopropylamino chlorides in the presence of sodium hydroxide, followed by ligation with dicyclohexylcarbodiimide. The compound adopts a centrosymmetric conformation due to the presence of two chiral centers at C3 and C4 positions on the pyridyl ring. The active site consists of an aromatic ring with three substituents, one of which is an amide group. This chemical transformation occurs through a nucleophilic attack by the amide group on an electrophilic carbonyl carbon atom.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 477.62 g/mol
• Fórmula: C₂₈H₃₁NO₄S
• Pureza: Min. 95%
• Color/Forma: Powder