Boc-4-cyano-L-phenylalanine

CAS: 131724-45-3

Ref. 3D-FB48006

Información del producto

• Nombre: Boc-4-cyano-L-phenylalanine
• Sinónimos: Boc-L-Phe(4-CN)-OHBoc-p-cyano-L-Phe-OH(S)-Boc-2-amino-(4-cyanophenyl)propanoic acid, (2S)-2-(tert-Butoxycarbonylamino)-3-(4-cyanophenyl)propanoic acid, (2S)-2-[(tert-Butoxycarbonyl)amino]-3-(4-cyanophenyl)propionic acid, (2S)-2-[(tert-butoxycarbonyl)amino]-3-(4-cyanophenyl)propanoate, (2S)-3-(4-Cyanophenyl)-2-(tert-butoxycarbonylamino)propanoic acid, (S)-2-[(tert-Butoxycarbonyl)amino]-3-(4-cyanophenyl)propanoic acid, (S)-2-[(tert-Butoxycarbonyl)amino]-3-(4-cyanophenyl)propionic acid, 4-Cyano-N-[(1,1-dimethylethoxy)carbonyl]-<span class="text-smallcaps">L</span>-phenylalanine, <span class="text-smallcaps">L</span>-Phenylalanine, 4-cyano-N-[(1,1-dimethylethoxy)carbonyl]-, Boc-4-Cyano-L-phenylalanine, Boc-L-4-Cyanophe, Boc-L-4-Cyanophenylalanine, Boc-L-Phe(4-Cn), Boc-L-Phe(4-Cn)-Oh, Boc-P-Cyano-L-Phe-Oh, Boc-P-Cyano-L-Phenylalanine, Boc-Phe(4-Cn)-Oh, Boc-Phe(P-Cn)-Oh, N-(tert-butoxycarbonyl)-4-cyano-D-phenylalanine, N-(tert-butoxycarbonyl)-4-cyano-L-phenylalanine, 4-Cyano-N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanine, L-Phenylalanine, 4-cyano-N-[(1,1-dimethylethoxy)carbonyl]-

Descripción

Boc-4-cyano-L-phenylalanine is a prodrug that is converted to phenylacetate, the active form, by esterases in the body. It is used as an anti-tuberculosis drug that enters cells and inhibits protein synthesis. The 4-cyano group on the Boc-4-cyano-L-phenylalanine molecule makes it resistant to modification from reactive oxygen species and prevents it from being metabolized by cytochrome P450 enzymes. Boc-4-cyano-L-phenylalanine has been shown to be more potent than other prodrugs for the treatment of tuberculosis because it can inhibit protein synthesis at millimolar concentrations. This agent also has a high uptake into cells and does not require glutathione for activation or inactivation.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 290.31 g/mol
• Fórmula: C₁₅H₁₈N₂O₄
• Pureza: Min. 95%