Bedaquiline fumarate

CAS: 845533-86-0

Ref. 3D-FB71553

Información del producto

• Nombre: Bedaquiline fumarate
• Sinónimos: (1R,2S)-1-(6-Bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol fumarate, (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-ol,(E)-but-2-enedioic acid, (4R,12aS)-7-(benzyloxy)-9-bromo-4-methyl-3,4-dihydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-6,8(12H,12aH)-dione, 3-Quinolineethanol, 6-bromo-α-[2-(dimethylamino)ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl-, (αS,βR)-, (2E)-2-butenedioate (1:1) (salt), R 403323, Sirturo

Descripción

Bedaquiline fumarate is the salt form of bedaquiline, a diarylquinoline molecule with an ATP synthetase inhibitory activity. Bedaquiline fumarate is an FDA-approved drug for the oral treatment of multidrug-resistant tuberculosis. Bedaquiline fumarate acts by inhibiting the activity of the ATP synthetase in the pathogenic bacterium Mycobacterium tuberculosis, even in the case of multiple antibiotic resistant strains.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 671.58 g/mol
• Fórmula: C₃₂H₃₁BrN₂O₂•C₄H₄O₄
• Pureza: Min. 97 Area-%
• Color/Forma: White Off-White Powder