1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone

CAS: 1378387-81-5

Ref. 3D-FB95439

Información del producto

• Nombre: 1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone
• Sinónimos: 1-(7-Bromo-9,9-difluorofluoren-2-yl)-2-chloroethanone, 1-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloro-Ethanone, Ethanone, 1-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloro-

Descripción

1-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone is a target product that is synthesized from 2-amino-5 bromobenzoic acid and chlorination of phenylboronic acid. The synthesis of this compound involves the diazotization of 1-(7-bromo-9,9 difluoro 9H fluoren 2 yl) ethanone with sodium nitrite in the presence of hydrochloric acid and sodium hydroxide. This compound is then coupled with 2 chloroethanol to form the title product. The coupling reaction includes stirring at room temperature for 6 hours with sodium carbonate as a base. The chlorination reaction follows by adding bromine dropwise to a solution of the target product in a solvent such as ethanol or acetonitrile. The ester hydrolysis occurs when the target product

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 357.58 g/mol
• Fórmula: C₁₅H₈BrClF₂O
• Pureza: Min. 95%