2-Chlorobenzoyl acetonitrile
CAS: 40018-25-5
Ref. 3D-FC10502
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Información del producto
- (2-Chlorophenyl)cyanomethyl ketone
- 2-Chloro-β-oxobenzenepropanenitrile
- 3-(2-Chlorophenyl)-3-Oxopropanenitrile
- 3-Oxo-3-(2-chlorophenyl)propanenitrile
- Acetonitrile, (o-chlorobenzoyl)-
- Benzenepropanenitrile, 2-Chloro-Beta-Oxo-
- Benzenepropanenitrile, 2-chloro-β-oxo-
- o-Chloro-ω-cyanoacetophenone
- o-Chlorobenzoylacetonitrile
- o-Chlorophenacyl cyanide
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2-Chlorobenzoyl acetonitrile is an oxime that can be synthesized by the base-catalyzed condensation of benzaldehyde and nitroethane. This reaction is followed by treatment with triethyl orthoformate, which leads to the formation of an imine intermediate. The imine is hydrolyzed to yield 2-chlorobenzamide and acetonitrile, which then reacts with amines to form a lactam. In order to obtain 2-chlorobenzoyl acetonitrile from this intermediate, a chloride must be added in order to break the lactam ring. Yields are typically low due to the high reactivity of the intermediate. Chemists have also shown that this compound exhibits a fluorescence response when exposed to light in the ultraviolet range.
2-Chlorobenzoyl acetonitrile has been used as a synthetic intermediate for other compounds such as piperazine, stator and
Propiedades químicas
Consulta técnica sobre: 3D-FC10502 2-Chlorobenzoyl acetonitrile
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