Cyclo(-Arg-Gly-Asp-D-Phe-Cys) acetate salt

CAS: 862772-11-0

Ref. 3D-FC110008

Información del producto

• Nombre: Cyclo(-Arg-Gly-Asp-D-Phe-Cys) acetate salt
• Sinónimos: c(RGDfC), avb3 Integrin Binding Cyclic RGD Peptide

Descripción

Cyclo(-Arg-Gly-Asp-D-Phe-Cys) acetate salt is a peptide that has been modified to be an active targeting agent. It is an amphipathic molecule that can be used to deliver therapeutic agents specifically to cancer cells. Cyclo(-Arg-Gly-Asp-D-Phe-Cys) acetate salt is conjugated to a drug and is taken up by cells through the process of endocytosis. Once inside the cell, the drug is released and binds with the cell membrane, which leads to cell death. The uptake of this peptide has been shown to be pH dependent; it is taken up more readily in acidic environments than in neutral or alkaline environments. This peptide has also been shown to have cytotoxic effects on both MFC7 cells and rat liver cells.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 578.64 g/mol
• Fórmula: C₂₄H₃₄N₈O₇S
• Pureza: Min. 95%
• InChI: InChI=1S/C24H34N8O7S/c25-24(26)27-8-4-7-14-20(36)28-11-18(33)29-16(10-19(34)35)22(38)31-15(9-13-5-2-1-3-6-13)21(37)32-17(12-40)23(39)30-14/h1-3,5-6,14-17,40H,4,7-12H2,(H,28,36)(H,29,33)(H,30,39)(H,31,38)(H,32,37)(H,34,35)(H4,25,26,27)
• Clave InChI: InChIKey=WNYJVAMZRBTOPE-UHFFFAOYSA-N
• SMILES: NC(N)=NCCCC1NC(=O)C(CS)NC(=O)C(Cc2ccccc2)NC(=O)C(CC(=O)O)NC(=O)CNC1=O