2-Chloropyridine-4-boronic acid

CAS: 458532-96-2

Ref. 3D-FC11490

Información del producto

• Nombre: 2-Chloropyridine-4-boronic acid
• Sinónimos: 2-Chloro-4-pyridylboronic acid2-Chloro-4-pyridineboronic acid2-Chloro-4-pyridinylboronic acid, (2-Chloro-4-pyridyl)boronic acid, (2-Chloropyridin-4-yl)boronic acid, 2-Chloro-4-pyridylboronic acid, B-(2-Chloro-4-pyridinyl)boronic acid, Boronic acid, (2-chloro-4-pyridinyl)-, Boronic acid, (2-chloro-4-pyridinyl)- (9CI), Boronic acid, B-(2-chloro-4-pyridinyl)

Descripción

2-Chloropyridine-4-boronic acid is a nicotinic acetylcholine receptor antagonist that has been shown to be effective against trypanosomiasis. It blocks the binding of acetylcholine to its receptor, which prevents the propagation of an action potential in the postsynaptic cell. 2-Chloropyridine-4-boronic acid inhibits the enzymes cyclooxygenase and prostaglandin synthase, which are involved in inflammation. 2-Chloropyridine-4-boronic acid is potent and selective for nicotinic acetylcholine receptors, but it also binds to other sites on the enzyme. The molecular modeling studies have shown that this compound has a pharmacophore that can be used as a guide for drug design.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 157.36 g/mol
• Fórmula: C₅H₅BClNO₂
• Pureza: Min. 95%