2-Chloro 7H-Pyrrolo[2,3-d]pyrimidine

CAS: 335654-06-3

Ref. 3D-FC11980

Información del producto

• Nombre: 2-Chloro 7H-Pyrrolo[2,3-d]pyrimidine
• Sinónimos: 7H-pyrrolo[2,3-d]pyrimidine,2-chloro-, 1H-Pyrrolo[2,3-d]pyrimidine, 2-chloro-, 2-Chloro-1H-pyrrolo[2,3-d]pyrimidine
• CAS: 335654-06-3

Descripción

2-Chloro 7H-Pyrrolo[2,3-d]pyrimidine is a pyrrolopyrimidine that inhibits the transcription factor NF-κB. It has been shown to inhibit the transcription of IL-4 and IL-5 in eosinophils. This inhibition was found to be mediated by the inhibition of NF-κB activity. The molecule has also been shown to have antiinflammatory properties in vitro. 2-Chloro 7H-Pyrrolo[2,3-d]pyrimidine is orally bioavailable and can be used for research purposes. In addition, this molecule can be synthesized using palladium catalysis in crosscoupling reactions.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 153.57 g/mol
• Fórmula: C₆H₄ClN₃
• Pureza: Min. 95%
• InChI: InChI=1S/C6H4ClN3/c7-6-9-3-4-1-2-8-5(4)10-6/h1-3H,(H,8,9,10)
• Clave InChI: InChIKey=HJOQGBBHVRYTDX-UHFFFAOYSA-N
• SMILES: Clc1ncc2cc[nH]c2n1