4-Chloro-2-(methylsulfonyl)pyrimidine

CAS: 97229-11-3

Ref. 3D-FC142333

Información del producto

• Nombre: 4-Chloro-2-(methylsulfonyl)pyrimidine
• Sinónimos: Pyrimidine, 4-chloro-2-(methylsulfonyl)-

Descripción

4-Chloro-2-(methylsulfonyl)pyrimidine is a modification of the drug tak-659 with high oral bioavailability. It has been evaluated for its x-ray crystallographic properties, and found to have similar binding affinity to tyrosine kinases as tak-659. 4-Chloro-2-(methylsulfonyl)pyrimidine has also been shown to have permeability in human erythrocytes and an oral bioavailability of 2%. It is a potential candidate for the treatment of various types of cancer, including those that are resistant to currently available drugs, such as chronic myeloid leukemia or acute lymphoblastic leukemia.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 192.62 g/mol
• Fórmula: C₅H₅ClN₂O₂S
• Pureza: Min. 95%