6-Chloro-2-methylquinoline

CAS: 92-46-6

Ref. 3D-FC153110

Información del producto

• Nombre: 6-Chloro-2-methylquinoline
• Sinónimos: 6-Chloroquinaldine, 2-Methyl-6-chloroquinoline

Descripción

6-Chloro-2-methylquinoline (6CQ) is a decoupling agent that has shown antileukemia activity in vitro. It is synthesized by the cyclodehydration of 2,3,5-trichloro-1,4-benzoquinone with aniline. The proton nmr spectra of 6CQ exhibits resonances at δ 7.6 and 8.0 ppm. 6CQ undergoes oxidation to form quinolinium hydrochloride and benzene oxide under UV irradiation or exposure to air for long periods of time. These products are responsible for its cytotoxicity and leukemogenic activities.
6CQ also has high reactivity towards amines and its derivatives, which makes it a useful reagent for the synthesis of urethane polymers and other compounds containing amines or quinoline rings (e.g., chloroquine).

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 177.63 g/mol
• Fórmula: C₁₀H₈ClN
• Pureza: Min. 95%
• InChI: InChI=1S/C10H8ClN/c1-7-2-3-8-6-9(11)4-5-10(8)12-7/h2-6H,1H3
• Clave InChI: InChIKey=OCCIBGIEIBQGAJ-UHFFFAOYSA-N
• SMILES: Cc1ccc2cc(Cl)ccc2n1