
2-Chloro-3-methylbenzonitrile
CAS: 15013-71-5
Ref. 3D-FC154547
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Información del producto
- Benzonitrile, 2-Chloro-3-Methyl-
2-Chloro-3-methylbenzonitrile is a metabolite of naphthalene, a chemical substance that can be found in cigarette smoke and vehicle exhaust. This product is used to detect the presence of naphthalene in urine samples. 2-Chloro-3-methylbenzonitrile has been detected in the urine of smokers with an average detection time of 6 hours. The compound undergoes biotransformation before excretion and can be converted into dihydroxylated metabolites. It also undergoes pharmacokinetic optimization through modifications by β-glucuronidase and monohydroxylation by glucuronyl transferases. A study conducted on rats concluded that 2-chloro-3-methylbenzonitrile has no carcinogenic effects.
2CBM has been shown to inhibit the activity of β-glucuronidase and monohydroxylation by glucuronyl transferases which may lead to
Propiedades químicas
Consulta técnica sobre: 3D-FC154547 2-Chloro-3-methylbenzonitrile
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