Selonsertib
CAS:
Ref. 3D-FC157241
0.01g
Descatalogado
0.025g
Descatalogado
0.05g
Descatalogado
0.1g
Descatalogado
5mg
Descatalogado
250mg
Descatalogado
10mg
Descatalogado
25mg
Descatalogado
50mg
Descatalogado
100mg
Descatalogado
Producto descatalogado. Para consultas sobre productos similares, rellene nuestro formulario o envíenos un correo electrónico a .
Información del producto
Nombre:Selonsertib
Sinónimos:
- 5-(4Cyclopropyl- 1H- imidazol- 1- yl) - 2- fluoro- N- (6- (4- isopropyl- 4H- 1
- 2
- 4- triazol- 3- yl) pyridin- 2- yl) - 4- methylben zamide
Marca:Biosynth
Descripción:Selonsertib is a highly selective inhibitor of the ATP-binding cassette transporter (ABCA1) that belongs to the class of glp-1 analogues. It is used in combination with other drugs for the treatment of bowel disease, autoimmune diseases, and skin cancer. Selonsertib has been shown to be active against a number of cell types and is also effective in models of metabolic disorders such as hepatic steatosis and kidney fibrosis. Selonsertib blocks ABCA1 by binding to its ATP-binding site, inhibiting cholesterol efflux from cells. This drug may work by restoring mitochondrial membrane potential, which may help prevent or reverse cellular damage caused by oxidative stress.
Aviso:Nuestros productos están destinados únicamente para uso en laboratorio. Para cualquier otro uso, por favor contáctenos.
Propiedades químicas
Peso molecular:445.49 g/mol
Fórmula:C24H24FN7O
Pureza:Min. 95%
InChI:InChI=1S/C24H24FN7O/c1-14(2)32-13-27-30-23(32)19-5-4-6-22(28-19)29-24(33)17-10-21(15(3)9-18(17)25)31-11-20(26-12-31)16-7-8-16/h4-6,9-14,16H,7-8H2,1-3H3,(H,28,29,33)
Clave InChI:InChIKey=YIDDLAAKOYYGJG-UHFFFAOYSA-N
SMILES:Cc1cc(F)c(C(=O)Nc2cccc(-c3nncn3C(C)C)n2)cc1-n1cnc(C2CC2)c1