(R)-Carprofen

CAS: 52263-83-9

Ref. 3D-FC19824

Información del producto

• Nombre: (R)-Carprofen
• Sinónimos: (aR)-6-Chloro-a-methyl-9H-carbazole-2-acetic acid(-)-Carprofen(R)-(-)-Carprofen, 9H-Carbazole-2-aceticacid, 6-chloro-a-methyl-,(R)-, (-)-Carprofen, (R)-(-)-Carprofen, C 8011

Descripción

(R)-Carprofen is a nonsteroidal anti-inflammatory drug that is used to treat pain and inflammation associated with arthritis, as well as other conditions. It is one of the most potent inhibitors of prostaglandin synthesis in human serum, but it has only moderate potency in bile and little or no affinity for fatty acids. The inhibition potential of carprofen has been shown to be stereoselective, with the (S)-enantiomer being up to 10 times more potent than the (R)-enantiomer. Carprofen is metabolized by conjugation with glucuronic acid and excreted in urine. Carprofen also has an inhibitory effect on endogenous substances such as diazepam, which may be due to its ability to inhibit CYP3A4.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 273.71 g/mol
• Fórmula: C₁₅H₁₂ClNO₂
• Pureza: Min. 95%
• Color/Forma: White to off-white solid.
• InChI: InChI=1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)/t8-/m1/s1
• Clave InChI: InChIKey=PUXBGTOOZJQSKH-MRVPVSSYSA-N
• SMILES: C[C@@H](C(=O)O)c1ccc2c(c1)[nH]c1ccc(Cl)cc12