3-(4-Chlorobenzal)phthalide

Ref. 3D-FC20189

Información del producto

• Nombre: 3-(4-Chlorobenzal)phthalide
• Sinónimos: 3-[(4-Chlorophenyl)methylene]-1(3H)-isobenzofuranone3-(p-Chlorobenzylidene)phthalide
• Marca: Biosynth
• Descripción: 3-(4-Chlorobenzal)phthalide is an antihistamine that belongs to the class of phthalic amines. It is a white crystalline solid with a melting point of 207-208°C. 3-(4-Chlorobenzal)phthalide has been shown to be effective in inhibiting histamine release from mast cells and other cells in vitro, as well as in vivo. The compound inhibits the release of histamine by blocking the H1 receptor on cells, preventing the activation of G proteins and inhibition of adenylyl cyclase. 3-(4-Chlorobenzal)phthalide also blocks the H3 receptor, which may account for its sedative effects. This molecule has been shown to be safe for use in humans at doses up to 20 mg/kg, with no significant adverse effects reported. It is also used for analysis of phthalic amines and hydrazine derivatives.

Propiedades químicas

• Peso molecular: 256.68 g/mol
• Fórmula: C₁₅H₉ClO₂
• Pureza: Min. 95%
• Color/Forma: Solid
• InChI: InChI=1S/C15H9ClO2/c16-11-7-5-10(6-8-11)9-14-12-3-1-2-4-13(12)15(17)18-14/h1-9H/b14-9-
• Clave InChI: InChIKey=OHRFHJYUEWVXBD-ZROIWOOFSA-N
• SMILES: O=C1O/C(=C\c2ccc(Cl)cc2)c2ccccc21