9-(2-Chloro-ethyl)-9H-purin-6-ylamine
CAS: 19255-48-2
Ref. 3D-FC20234
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Información del producto
- 9-(2-Chloroethyl)adenineNSC 50715
- 9-(2-chloroethyl)-9H-purin-6-amine
9-(2-Chloro-ethyl)-9H-purin-6-ylamine is a nucleotide analog. It forms hydrogen bonds with DNA bases, which may be due to the chloride ion acting as an electron acceptor. This interaction leads to cross-linking and yields low molecular weight analogs in the presence of diallylamine. 9-(2-Chloro-ethyl)-9H-purin-6-ylamine has also been shown to form hydrophobic interactions with the phosphate groups in DNA. This synthetic drug is often used in cancer chemotherapy and can be synthesized from 2,4,6-trichloropyrimidine and 1-(2 chloroethyl)pyridinium iodide.
Propiedades químicas
Consulta técnica sobre: 3D-FC20234 9-(2-Chloro-ethyl)-9H-purin-6-ylamine
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