c3-Chloro-4-methylpyridine
CAS: 72093-04-0
Ref. 3D-FC33804
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| 5g | A consultar | ||
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Información del producto
- 3-Chloro-4-picoline
- 4-Picoline, 3-chloro-
- Pyridine, 3-Chloro-4-Methyl-
C3-Chloro-4-methylpyridine is an intermediate in the synthesis of tofacitinib, a drug used to treat rheumatoid arthritis. C3-Chloro-4-methylpyridine is prepared by asymmetric hydrogenation of 3,5-dichloro-2,6-dimethylaniline. This process proceeds through an acylation step followed by an asymmetric hydrogenation. The reaction mixture consists of the desired product and a significant amount of 3,5 dichloropyridine. The desired product can be isolated from this mixture using column chromatography or recrystallization.
Propiedades químicas
Consulta técnica sobre: 3D-FC33804 c3-Chloro-4-methylpyridine
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