4-Chloro Kynurenine

CAS: 75802-84-5

Ref. 3D-FC34922

Información del producto

• Nombre: 4-Chloro Kynurenine
• Sinónimos: 2-Amino-4-(2-Amino-4-Chlorophenyl)-4-Oxobutanoic Acid, Benzenebutanoic acid, α,2-diamino-4-chloro-γ-oxo-, 2-Amino-4-(2-amino-4-chlorophenyl)-4-oxobutanoic acid, Benzenebutanoic acid, α,2-diamino-4-chloro-γ-oxo-, (±)-, α,2-Diamino-4-chloro-γ-oxobenzenebutanoic acid

Descripción

4-Chloro Kynurenine is an aminotransferase activator that has been shown to produce antidepressant responses in animals. It is also a prodrug of rapamycin, which acts as an immunosuppressant and prevents the uptake of glutamate. 4-Chloro Kynurenine is used for the treatment of treatment-resistant depression. It inhibits glycogen synthase kinase-3 (GSK-3) and enhances the uptake of glutamate by organic anion transporters (OATs). This inhibition increases neurotrophic factors such as brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF). These findings suggest that 4-chloro kynurenine may be a novel drug for the treatment of depression.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 242.66 g/mol
• Fórmula: C₁₀H₁₁ClN₂O₃
• Pureza: Min. 95%
• Color/Forma: Off-White Powder
• InChI: InChI=1S/C10H11ClN2O3/c11-5-1-2-6(7(12)3-5)9(14)4-8(13)10(15)16/h1-3,8H,4,12-13H2,(H,15,16)
• Clave InChI: InChIKey=HQLHZNDJQSRKDT-UHFFFAOYSA-N
• SMILES: Nc1cc(Cl)ccc1C(=O)CC(N)C(=O)O