4-Chloro-6,7-dimethoxyquinoline

CAS: 35654-56-9

Ref. 3D-FC42168

Información del producto

• Nombre: 4-Chloro-6,7-dimethoxyquinoline
• Marca: Biosynth
• Descripción: 4-Chloro-6,7-dimethoxyquinoline (4C6DMQ) is a potent inhibitor of the growth of prostate cancer cells. 4C6DMQ is an analog of chloropropyl chloride, which inhibits the growth of epidermal growth factor receptor (EGFR). The binding site for 4C6DMQ on EGFR is the same as that for chloropropyl chloride. 4C6DMQ inhibits EGFR by preventing the activation of downstream signaling cascades, leading to a decrease in cell proliferation and tumor size. The IC50 values for 4C6DMQ are approximately 10 times higher than those for chloropropyl chloride. This drug has been shown to be more potent than other inhibitors of EGFR such as erlotinib and gefitinib.

Propiedades químicas

• Peso molecular: 223.66 g/mol
• Fórmula: C₁₁H₁₀ClNO₂
• Pureza: Min. 95%
• Color/Forma: White Powder
• InChI: InChI=1S/C11H10ClNO2/c1-14-10-5-7-8(12)3-4-13-9(7)6-11(10)15-2/h3-6H,1-2H3
• Clave InChI: InChIKey=WRVHQEYBCDPZEU-UHFFFAOYSA-N
• SMILES: COc1cc2nccc(Cl)c2cc1OC