7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepine-2-thione

CAS: 2898-13-7

Ref. 3D-FC46885

Información del producto

• Nombre: 7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepine-2-thione
• Sinónimos: Sulazepam, 2H-1,4-Benzodiazepine-2-thione, 7-chloro-1,3-dihydro-1-methyl-5-phenyl-, 7-Chloro-1-methyl-5-phenyl-1H-1,4-benzodiazepine-2(3H)-thione, 7-Chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepine-2-thione, 7-chloro-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepine-2-thione, Brn 0754372, Sulazepam [USAN:INN], Sulazepamum, Sulazepamum [INN-Latin], Unii-Nz779Q5S0W, W 3676, 5-24-04-00355 (Beilstein Handbook Reference), Sulazepam

Descripción

7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepine-2-thione (7CDMT) is a molecule that has been reconstituted in order to serve as an allosteric modulator. This compound is an analog of diazepam and has the same biological properties. 7CDMT binds to the benzodiazepine site on the GABA receptor and can be used for research purposes. It is a competitive antagonist of GABA at the benzodiazepine site, but also acts as an agonist at the fatty acid site. 7CDMT has been shown to have no effect on fatty alcohols or fatty acids. The activity index of this molecule is 0.913.
The product research study was conducted in rats with chronic drug treatment over 60 days and showed that 7CDMT had no observable toxic effects, but did cause convulsions

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 300.81 g/mol
• Fórmula: C₁₆H₁₃ClN₂S
• Pureza: Min. 95%
• Color/Forma: Powder
• InChI: InChI=1S/C16H13ClN2S/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3
• Clave InChI: InChIKey=MWGWTOPCKLQYEU-UHFFFAOYSA-N
• SMILES: CN1C(=S)CN=C(c2ccccc2)c2cc(Cl)ccc21