Carmofur

CAS: 61422-45-5

Ref. 3D-FC60423

Información del producto

• Nombre: Carmofur
• Sinónimos: 5-Fluoro-1-hexylcarbamoyluracil
• Marca: Biosynth
• Descripción: Carmofur is a fluorouracil derivative that interferes with nucleotide metabolism and consequently with synthesis of RNA and DNA, leading to cytotoxic and antineoplastic effects. Carmofur inhibits also other enzymes such as lysosomal acid ceramidase and the main protease from coronaviruses. For the SARS-CoV-2 main protease Mpro, carmofur was characterised as a covalent inhibitor with IC50 of 1.82 μM and EC50 of 24.30 μM.

Propiedades químicas

• Peso molecular: 257.26 g/mol
• Fórmula: C₁₁H₁₆FN₃O₃
• Pureza: Min. 95%
• Color/Forma: White Powder
• InChI: InChI=1S/C11H16FN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)
• Clave InChI: InChIKey=AOCCBINRVIKJHY-UHFFFAOYSA-N
• SMILES: CCCCCCNC(=O)n1cc(F)c(=O)[nH]c1=O