Corynanthine

CAS: 483-10-3

Ref. 3D-FC71579

Información del producto

• Nombre: Corynanthine
• Sinónimos: Benz[g]indolo[2,3-a]quinolizine, yohimban-16-carboxylic acid deriv., Corynanthin, Methyl (16Beta,17Alpha)-17-Hydroxyyohimban-16-Carboxylate, NSC 407306, Rauhimbin, Rauhimbine, Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16β,17α)-, Yohimban-16β-carboxylic acid, 17α-hydroxy-, methyl ester

Descripción

Corynanthine is a quinazoline compound that is used as a radioprotectant to prevent damage to the heart, lungs, and other tissues when high doses of radiation are given. Corynanthine has been shown to bind to the 2-adrenergic receptor in human serum and inhibit the production of serum prolactin levels. It also has an antagonistic effect on the neurokinin-1 receptor, which inhibits dopamine release from nerve terminals. This drug shows no toxicity in animals at doses up to 10 times the maximum human dose.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 354.44 g/mol
• Fórmula: C₂₁H₂₆N₂O₃
• Pureza: Min. 90 Area-%
• Color/Forma: Beige Powder
• InChI: InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19-/m0/s1
• Clave InChI: InChIKey=BLGXFZZNTVWLAY-DKJBZYCGSA-N
• SMILES: COC(=O)[C@@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12