4,6-Dihydroxypyrimidine

CAS: 1193-24-4

Ref. 3D-FD11328

Información del producto

• Nombre: 4,6-Dihydroxypyrimidine
• Sinónimos: 4(1H)-Pyrimidinone, 6-hydroxy-, 4(3H)-Pyrimidinone, 6-hydroxy-, 4,6-Dihydroxy Pyrimidine, 4,6-Dihydroxypyrimidine (4,6-DHP), 4,6-Pyrimidinediol, 6-Hydroxy-1H-pyrimidin-4-one, 6-Hydroxy-4(3H)-pyrimidinone, 6-Hydroxypyrimidin-4(3H)-one, NSC 22838, Pyrimidine-4,6-diol

Descripción

4,6-Dihydroxypyrimidine is a competitive inhibitor of the bacterial enzyme DNA gyrase. It binds to the ATP-binding site and blocks the conversion of ATP to ADP. This leads to inhibition of the DNA replication process. 4,6-Dihydroxypyrimidine has shown inhibition constants against various bacterial strains. The kinetic data indicate that this compound is a noncompetitive inhibitor for DNA gyrase. 4,6-Dihydroxypyrimidine also binds to sodium hydroxide solution and forms a Langmuir adsorption isotherm that can be described by an equation with a single binding site. The chemical structure of 4,6-dihydroxypyrimidine consists of three atoms: two hydrogen atoms and one oxygen atom. This molecule has been found in electrochemical impedance spectroscopy experiments using methanol solvent as an electrolyte and monosodium salt as a supporting electrolyte.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 112.09 g/mol
• Fórmula: C₄H₄N₂O₂
• Pureza: Min. 95%
• Color/Forma: Yellow Powder