4,6-Dichloronicotinaldehyde
CAS: 1060811-62-2
Ref. 3D-FD143587
1g | A consultar | ||
2g | A consultar | ||
100mg | A consultar | ||
250mg | A consultar | ||
500mg | A consultar |
Información del producto
- 4,6-dichloro-3-Pyridinecarboxaldehyde
- 4,6-Dichloropyridine-3-carboxaldehyde
4,6-Dichloronicotinaldehyde is a potent inhibitor of the enzyme kinase Plk1. It inhibits the activity of this enzyme by binding to the ATP-binding site, thereby blocking ATP hydrolysis and inhibiting cell division. The IC50 for 4,6-dichloronicotinaldehyde is in the nanomolar range. This compound has been shown to inhibit cells with a specific phenotype, such as human mammary epithelial cells (HMEC), while not affecting other cell types such as HeLa cells. 4,6-Dichloronicotinaldehyde has also been shown to be effective against low nanomolar concentrations of Plk1 in vitro and in vivo.
Propiedades químicas
Consulta técnica sobre: 3D-FD143587 4,6-Dichloronicotinaldehyde
Si desea solicitar un presupuesto o realizar un pedido, por favor añada los productos deseados a su carrito y solicite un presupuesto o pedido desde el carrito. Es más rápido, más barato, y podrá beneficiarse de los descuentos y las ventajas disponibles.