1,2-Dihydrobudesonide

CAS: 137174-25-5

Ref. 3D-FD146154

Información del producto

• Nombre: 1,2-Dihydrobudesonide
• CAS: 137174-25-5

Descripción

1,2-Dihydrobudesonide is a synthetic glucocorticosteroid that has a molecular structure similar to prednisolone. It is used for the treatment of inflammatory skin conditions such as eczema and psoriasis. 1,2-Dihydrobudesonide has been shown to have a high oral bioavailability and low systemic bioavailability. The molecule is metabolized in the liver to produce hydrocortisone, which accounts for its oral bioavailability. 1,2-Dihydrobudesonide is classified as an acetal because it contains an acetal linkage between the 16-carbon (C16) steroid nucleus and the 17-carbon (C17) side chain. This connection results in a more stable molecule than desonide, which is not acetalated. In vitro data indicates that 1,2-dihydrobudesonide has a lower binding affinity with human liver cytosolic receptors than des

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 432.55 g/mol
• Fórmula: C₂₅H₃₆O₆
• Pureza: Min. 95%