1,2-Dihydro-4-methyl-2-oxo-3-pyridinecarbonitrile
CAS: 93271-59-1
Ref. 3D-FD150345
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Información del producto
- 3-Pyridinecarbonitrile, 1,2-dihydro-4-methyl-2-oxo-
- 4-Methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
- 2-Hydroxy-4-methylpyridine-3-carbonitrile
1,2-Dihydro-4-methyl-2-oxo-3-pyridinecarbonitrile (1) is a synthon that can be used in the synthesis of nevirapine and oxychloride. It contains an active methylene group which is accessible for substitution reactions. 1,2-Dihydro-4-methyl-2-oxo-3-pyridinecarbonitrile can be synthesized by amide formation between cyanoacetamide (2) and an isopropyl Grignard reagent (3). This reaction yields a molecule containing a pyridine ring. The industrial process involves the use of sodium hypochlorite to oxidize 1 to 2.
Propiedades químicas
Consulta técnica sobre: 3D-FD150345 1,2-Dihydro-4-methyl-2-oxo-3-pyridinecarbonitrile
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