2,6-Dibromopurine

CAS: 1196-41-4

Ref. 3D-FD150431

Información del producto

• Nombre: 2,6-Dibromopurine
• Sinónimos: 1H-Purine, 2,6-dibromo-, 2,6-Dibromo-9H-purine, 2,6-dibromo-5H-purine, 2,6-dibromo-7H-purine, 9H-Purine, 2,6-dibromo-, NSC 45151, Purine, 2,6-dibromo-

Descripción

2,6-Dibromopurine is a purine that is found in caffeine. It is an analogue of adenosine and inhibits the growth of human cells lines by competitively inhibiting the incorporation of deoxyadenosine into ribonucleotides. The kinetic study showed that 2,6-dibromopurine has a higher affinity for the adenosine receptor than adenosine. The effect of 2,6-dibromopurine on cellular metabolism has been shown to be stereospecific as it can inhibit both deoxyadenosine kinase and adenylate kinase activities. This drug also inhibited hematopoietic cells in vitro, which may be due to its ability to inhibit ribonucleotide reductase activity.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 277.9 g/mol
• Fórmula: C₅H₂Br₂N₄
• Pureza: Min. 95%
• InChI: InChI=1S/C5H2Br2N4/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H,8,9,10,11)
• Clave InChI: InChIKey=YPFDNCJJFMAZPJ-UHFFFAOYSA-N
• SMILES: Brc1nc(Br)c2[nH]cnc2n1