(4R,5S,6S)-3-[[4-[(5S)-2,5-Dihydro-5-methyl-1H-pyrrol-3-yl]-2-thiazolyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3. 2.0]hept-2-ene-2-carboxylicacid

CAS: 426253-04-5

Ref. 3D-FD152101

Información del producto

• Nombre: (4R,5S,6S)-3-[[4-[(5S)-2,5-Dihydro-5-methyl-1H-pyrrol-3-yl]-2-thiazolyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3. 2.0]hept-2-ene-2-carboxylicacid
• Sinónimos: Razupenem
• Marca: Biosynth
• Descripción: Acyl-CoA thiolase (ACOT) is a bacterial enzyme that catalyzes the reaction of fatty acyl-CoA with CoA to form CoA esters and free fatty acids. The ACOT gene has been identified as an important virulence factor in Staphylococcus aureus isolates. Researchers have demonstrated that ACOT inhibitors can be used to treat bacterial infections by inhibiting the growth of bacteria and preventing them from forming biofilms, which are protective colonies of bacteria that adhere to surfaces and release substances harmful to the host. Gatifloxacin is an example of an ACOT inhibitor that has been shown to be active against methicillin-resistant Staphylococcus aureus (MRSA) and P. aeruginosa, although it is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex.

Propiedades químicas

• Peso molecular: 407.51 g/mol
• Fórmula: C₁₈H₂₁N₃O₄S₂
• Pureza: Min. 95%