(4aS,5aR,10aR,11aS,15aR,15bS,16E,18E,19aS,19bR)-2,3,4,4a,5,5a,6,7,8,9,10,10a,11,11a,12,13,14,15,15a,15b,19a,19b-Docosahydro-1H-diind eno[2,1-f:1’,2’-l][1,5]diazacyclotridecine

CAS: 112455-84-2

Ref. 3D-FD158727

Información del producto

• Nombre: (4aS,5aR,10aR,11aS,15aR,15bS,16E,18E,19aS,19bR)-2,3,4,4a,5,5a,6,7,8,9,10,10a,11,11a,12,13,14,15,15a,15b,19a,19b-Docosahydro-1H-diind eno[2,1-f:1’,2’-l][1,5]diazacyclotridecine
• Sinónimos: Papuamine(-)-Papuamine, (-)-Papuamine, (4aS,5aR,10aR,11aS,15aR,15bS,16E,18E,19aS,19bR)-2,3,4,4a,5,5a,6,7,8,9,10,10a,11,11a,12,13,14,15,15a,15b,19a,19b-Docosahydro-1H-diindeno[2,1-f:1′,2′-l][1,5]diazacyclotridecine, 112455-84-2, 1H-Diindeno[2,1-f:1′,2′-l][1,5]diazacyclotridecine, 2,3,4,4a,5,5a,6,7,8,9,10,10a,11,11a,12,13,14,15,15a,15b,19a,19b-docosahydro-, (4aS,5aR,10aR,11aS,15aR,15bS,16E,18E,19aS,19bR)-, 1H-Diindeno[2,1-f:1′,2′-l][1,5]diazacyclotridecine, 2,3,4,4a,5,5a,6,7,8,9,10,10a,11,11a,12,13,14,15,15a,15b,19a,19b-docosahydro-, [4aS-(4aR*,5aS*,10aS*,11aR*,15aS*,15bR*,16E,18E,19aR*,19bS*)]-, [4aS-(4aR*,5aS*,10aS*,11aR*,15aS*,15bR*,16E,18E,19aR*,19bS*)]-2,3,4,4a,5,5a,6,7,8,9,10,10a,11,11a,12,13,14,15,15a,15b,19a,19b-Docosahydro-1H-diindeno[2,1-f:1',2'-1][1,5]diazacyclotridecine

Descripción

(4aS,5aR,10aR,11aS,15aR,15bS,16E,18E,19aS,19bR)-2,3,4,4a,5,5a,6,7,8,9,10,10a,11,,11 a,,12,,13,,14,,15,,15 a,, 15 b-Docosahydro-1H-diindeno[2′1′’2’]1”5]diazacyclotridecine is a cytotoxic and antimycobacterial agent that belongs to the group of indole-derived natural products. It inhibits the mitochondrial respiratory chain and induces apoptosis in cancer cells.

In addition to its potent cytotoxicity against cancer cells in culture and its ability to inhibit autophagy in mcf-7 cells (an immortalized mouse mammary tumor cell line

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 368.6 g/mol
• Fórmula: C₂₅H₄₀N₂
• Pureza: Min. 95%
• InChI: InChI=1S/C25H40N2/c1-3-10-20-18(8-1)16-24-22(20)12-5-6-13-23-21-11-4-2-9-19(21)17-25(23)27-15-7-14-26-24/h5-6,12-13,18-27H,1-4,7-11,14-17H2/b12-5-,13-6-/t18-,19-,20+,21+,22-,23-,24+,25+/m0/s1
• Clave InChI: InChIKey=ZKTFUNZCYRUILZ-JJDAYECRSA-N
• SMILES: C1=C/[C@@H]2[C@@H](C[C@@H]3CCCC[C@H]32)NCCCN[C@@H]2C[C@@H]3CCCC[C@H]3[C@@H]2/C=C/1