Denbufylline

CAS: 57076-71-8

Ref. 3D-FD21036

Información del producto

• Nombre: Denbufylline
• Sinónimos: 1,3-Di-n-butyl-7-[2'-oxopropyl)xanthineBRL 308921,3-Dibutyl-3,7-dihydro-7-(2-oxopropyl)-1H-purine-2,6-dione, 1,3-Di-n-butyl-7-(2-oxopropyl)xanthine, 1,3-Dibutyl-3,7-dihydro-7-(2-oxopropyl)-1H-purine-2,6-dione, 1,3-dibutyl-7-(2-oxopropyl)-3,7-dihydro-1H-purine-2,6-dione, 1H-Purine-2,6-dione, 1,3-dibutyl-3,7-dihydro-7-(2-oxopropyl)-, 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dibutyl-7-(2-oxopropyl)-, 3,7-Dihydro-1,3-dibutyl-7-(2-oxopropyl)-1H-purine-2,6-dione, 7-Acetonyl-1,3-dibutylxanthine, Brl 30892, Denbufilina, Denbufilina [Spanish], Denbufylline [INN:BAN], Denbufyllinum, Denbufyllinum [Latin], Denbutyline, Denbutylline, Unii-04B949Ko6F

Descripción

Denbufylline is a chiral compound that acts as an agonist of the 2-adrenergic receptor. It also has been shown to increase calcium levels in the cytosol, which may be due to its ability to inhibit phosphodiesterase. Denbufylline has been shown to have a number of pharmacological effects, including stimulation of contractions in rat heart and detrusor muscle, and inhibition of intestinal motility. The drug also increases nucleotide levels in cardiac tissue, but not in skeletal muscle or liver tissue. Denbufylline is metabolized by cytochrome P450 enzymes into metabolites with similar pharmacological properties. This drug has been shown to cause bradycardia and hypotension in humans at high doses.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 320.39 g/mol
• Fórmula: C₁₆H₂₄N₄O₃
• Pureza: Min. 95%
• Color/Forma: Powder
• InChI: InChI=1S/C16H24N4O3/c1-4-6-8-19-14-13(18(11-17-14)10-12(3)21)15(22)20(16(19)23)9-7-5-2/h11H,4-10H2,1-3H3
• Clave InChI: InChIKey=HJPRDDKCXVCFOH-UHFFFAOYSA-N
• SMILES: CCCCn1c(=O)c2c(ncn2CC(C)=O)n(CCCC)c1=O